Classic Southern Meatloaf is the ultimate comfort food. Juicy, flavorful ground beef mixed with the perfect blend of Southern seasonings, topped with a sweet and tangy glaze that caramelizes beautifully in the oven. This isn’t dry or bland — it’s the kind of meatloaf that brings everyone back for seconds.
This recipe delivers that old-fashioned, from-scratch taste just like Grandma used to make. It’s easy to prepare, budget-friendly, and perfect for family dinners or meal prep.
Prep Time: 15 minutes
Cook Time: 55–65 minutes
Total Time: 1 hour 20 minutes
Servings: 6–8
Why This Recipe Works
- Combination of ground beef and pork for maximum juiciness and flavor
- Vegetables sautéed for deeper taste (not left raw)
- Classic Southern glaze that’s sweet, tangy, and sticky
- Free-form shape bakes faster and gives more crispy edges
Ingredients
For the Meatloaf:
- 1 ½ lbs ground beef (80/20)
- ½ lb ground pork
- 1 medium onion, finely diced
- 1 green bell pepper, finely diced
- 3 cloves garlic, minced
- 1 cup breadcrumbs (or crushed saltine crackers)
- ½ cup milk
- 2 large eggs
- 2 tablespoons ketchup
- 1 tablespoon Worcestershire sauce
- 1 teaspoon salt
- 1 teaspoon black pepper
- 1 teaspoon smoked paprika
- ½ teaspoon dried thyme
- ½ teaspoon garlic powder
For the Glaze:
- ½ cup ketchup
- 3 tablespoons brown sugar
- 1 tablespoon yellow mustard
- 1 tablespoon apple cider vinegar
- 1 teaspoon Worcestershire sauce
Instructions
Step 1: Preheat & Prepare
Preheat your oven to 375°F (190°C). Line a baking sheet with parchment paper or lightly grease a loaf pan.
Step 2: Sauté Vegetables
In a skillet over medium heat, sauté the diced onion and green bell pepper for 5–6 minutes until softened. Add minced garlic and cook for 30 seconds. Remove from heat and let cool slightly.
Step 3: Mix the Meatloaf
In a large bowl, combine milk and breadcrumbs. Let sit for 2 minutes.
Add the ground beef, ground pork, sautéed vegetables, eggs, ketchup, Worcestershire sauce, salt, pepper, smoked paprika, thyme, and garlic powder.
Mix gently with your hands until just combined — do not overmix or the meatloaf will become tough.
Step 4: Shape & Glaze
Shape the mixture into a loaf on the prepared baking sheet (about 8×4 inches).
In a small bowl, mix all glaze ingredients. Spread half the glaze over the top and sides of the meatloaf. Reserve the rest for later.
Step 5: Bake
Bake for 45 minutes. Remove from oven, spread the remaining glaze on top, and return to oven for another 10–20 minutes, or until the internal temperature reaches 160°F (71°C).
Step 6: Rest & Serve
Let the meatloaf rest for 10–15 minutes before slicing. This helps it hold together and keeps it juicy.
Pro Tips for the Best Southern Meatloaf
- Don’t overmix — Gentle mixing keeps the texture tender.
- Use 80/20 beef — The fat content is essential for moisture.
- Add bacon — For extra Southern flair, mix in 4–5 slices of chopped cooked bacon.
- Make mini loaves — Divide into 4 small loaves for faster cooking and individual servings.
- Leftovers — Cold meatloaf sandwiches are a Southern favorite!
What to Serve with Southern Meatloaf
- Creamy Mashed Potatoes with gravy
- Southern Collard Greens or Green Beans
- Classic Buttermilk Biscuits
- Mac and Cheese
Storage & Reheating
- Refrigerator: Store in an airtight container for up to 4 days.
- Freezer: Wrap tightly and freeze for up to 3 months.
- Reheating: Warm slices in a 350°F oven or microwave with a little gravy to keep moist.
Frequently Asked Questions
Can I use all ground beef?
Yes, it will still be delicious. The pork just adds extra richness and moisture.
Why is my meatloaf dry?
Overmixing, using lean meat, or overcooking are the usual reasons. Check temperature at 160°F.
Can I make this ahead?
Yes! Assemble the meatloaf, cover, and refrigerate up to 24 hours before baking.
This Classic Southern Meatloaf with Glaze is hearty, flavorful, and brings pure comfort to the table. It’s a timeless recipe that never goes out of style.

